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An Innovative New Approach to Treating Autoimmune and Inflammatory Diseases Without Immunosuppression

Our Science

Our fully-human biologic drug platform combines RNases and DNases with an antibody Fc to remove extracellular nucleic acids including RNA, DNA and neutrophil extracellular traps (NETs), which restores homeostasis and resolves inflammation. We are applying this technology across multiple acute and chronic diseases with high unmet need. 

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Our Clinical Trial

Resolve is currently evaluating RSLV-132 in a Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Clinical Trial in Sjögren’s Disease.

News and Events

Novemeber 19, 2025

Resolve Therapeutics to Present at International Symposium on Circulating Nucleic Acids in Plasma and Serum (CNAPS)

May 28, 2025

Resolve Therapeutics and Duke Medical School Initiate Observational Study of Cell-free RNA in Polytrauma Patients.

May 13, 2024

Resolve Therapeutics Publishes Results of RSLV-132 Phase 2 Long COVID Study

May 13, 2024

Resolve Therapeutics Announces Publication of Lupus Clinical Trial Results

May 13, 2024

Resolve Therapeutics Announces Publication of Lupus Clinical Trial Results

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